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Robert C. Chang
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Journal Articles

Biomedical Manufacturing: A Review of the Emerging Research and Applications

Roland Chen, Robert C. Chang, Bruce Tai, Yong Huang, Burak Ozdoganlar, Wei Li, Albert Shih
Journal: Journal of Manufacturing Science and Engineering
Publisher: ASME
Article Type: Review Articles
J. Manuf. Sci. Eng. November 2020, 142(11): 110807.
Paper No: MANU-20-1080
https://doi.org/10.1115/1.4048043
Published Online: September 3, 2020
View Articletitled, Biomedical Manufacturing: A Review of the Emerging Research and Applications
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Topics: Additive manufacturing, Biological tissues, Biomedicine, Bioprinting, Cutting, Joining, Machining, Manufacturing, Printing, Bone
Proceedings Papers

Bioprinting of Liquid Hydrogel Precursors in a Support Bath by Analyzing Two Key Features: Cell Distribution and Shape Fidelity

Houzhu Ding, Robert C. Chang
Proc. ASME. MSEC2018, Volume 1: Additive Manufacturing; Bio and Sustainable Manufacturing, V001T05A017, June 18–22, 2018
Publisher: American Society of Mechanical Engineers
Paper No: MSEC2018-6675
https://doi.org/10.1115/MSEC2018-6675
View Paper titled, Bioprinting of Liquid Hydrogel Precursors in a Support Bath by Analyzing Two Key Features: Cell Distribution and Shape Fidelity
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Topics: Bioprinting, Hydrogels, Shapes, Biological tissues, Inks, Performance, Viscosity, Additive manufacturing, Density, Flow (Dynamics)
Journal Articles

Hyperspectral Imaging With Burn Contour Extraction for Burn Wound Depth Assessment

Houzhu Ding, Robert C. Chang
Journal: Journal of Engineering and Science in Medical Diagnostics and Therapy
Publisher: ASME
Article Type: Research-Article
ASME J of Medical Diagnostics. November 2018, 1(4): 041002.
Paper No: JESMDT-18-1016
https://doi.org/10.1115/1.4040470
Published Online: July 3, 2018
View Articletitled, Hyperspectral Imaging With Burn Contour Extraction for Burn Wound Depth Assessment
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Topics: Biological tissues, Imaging, Oxygen, Skin, Wounds, Algorithms, Regression analysis
Journal Articles

A Methodology for Quantifying Cell Density and Distribution in Multidimensional Bioprinted Gelatin–Alginate Constructs

Houzhu Ding, Filippos Tourlomousis, Robert C. Chang
Journal: Journal of Manufacturing Science and Engineering
Publisher: ASME
Article Type: Research-Article
J. Manuf. Sci. Eng. May 2018, 140(5): 051014.
Paper No: MANU-17-1463
https://doi.org/10.1115/1.4037572
Published Online: March 7, 2018
View Articletitled, A Methodology for Quantifying Cell Density and Distribution in Multidimensional Bioprinted Gelatin–Alginate Constructs
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Topics: Bioprinting, Density, Fibers, Gelatin, Hydrogels, Inks, Printing, Temperature, Viscosity, Shapes
Journal Articles

Investigation of Cellular Confinement in Three-Dimensional Microscale Fibrous Substrates: Fabrication and Metrology

Filippos Tourlomousis, William Boettcher, Houzhu Ding, Robert C. Chang
Journal: Journal of Micro and Nano-Manufacturing
Publisher: ASME
Article Type: Research-Article
J. Micro Nano-Manuf. June 2018, 6(2): 021003.
Paper No: JMNM-17-1055
https://doi.org/10.1115/1.4038803
Published Online: January 18, 2018
View Articletitled, Investigation of Cellular Confinement in Three-Dimensional Microscale Fibrous Substrates: Fabrication and Metrology
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Topics: Fibroblasts, Manufacturing, Metrology, Shapes, Stem cells, Adhesion, Microscale devices, Workflow, Electrospinning, Proteins
Proceedings Papers

A Methodology for Quantifying Cell Density and Distribution in Multidimensional Bioprinted Gelatin-Alginate Constructs

Houzhu Ding, Enyan Dai, Filippos Tourlomousis, Robert C. Chang
Proc. ASME. MSEC2017, Volume 4: Bio and Sustainable Manufacturing, V004T05A015, June 4–8, 2017
Publisher: American Society of Mechanical Engineers
Paper No: MSEC2017-2853
https://doi.org/10.1115/MSEC2017-2853
View Paper titled, A Methodology for Quantifying Cell Density and Distribution in Multidimensional Bioprinted Gelatin-Alginate Constructs
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Topics: Bioprinting, Density, Gelatin, Fibers, Viscosity, Inks, Printing, Biological tissues, Hydrogels, Struts (Engineering)
Proceedings Papers

Investigation of Cellular Confinement in 3D Microscale Fibrous Substrates: Fabrication and Metrology

Filippos Tourlomousis, William Boettcher, Houzhu Ding, Robert C. Chang
Proc. ASME. MSEC2017, Volume 4: Bio and Sustainable Manufacturing, V004T05A018, June 4–8, 2017
Publisher: American Society of Mechanical Engineers
Paper No: MSEC2017-3020
https://doi.org/10.1115/MSEC2017-3020
View Paper titled, Investigation of Cellular Confinement in 3D Microscale Fibrous Substrates: Fabrication and Metrology
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Topics: Manufacturing, Metrology, Microscale devices, Fibroblasts, Shapes, Adhesion, Bearings, Electrospinning, Fluorescence, Imaging
Journal Articles

Melt Electrospinning Writing Process Guided by a “Printability Number”

Filippos Tourlomousis, Houzhu Ding, Dilhan M. Kalyon, Robert C. Chang
Journal: Journal of Manufacturing Science and Engineering
Publisher: ASME
Article Type: Research-Article
J. Manuf. Sci. Eng. August 2017, 139(8): 081004.
Paper No: MANU-16-1345
https://doi.org/10.1115/1.4036348
Published Online: May 8, 2017
View Articletitled, Melt Electrospinning Writing Process Guided by a “Printability Number”
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Topics: Electrospinning, Equilibrium (Physics), Fibers, Flow (Dynamics), Manufacturing, Polymer melts, Printing, Temperature, Needles, Polymers
Proceedings Papers

Design of a Skin Grafting Methodology for Burn Wound Using an Additive Biomanufacturing System Guided by Hyperspectral Imaging

Houzhu Ding, Antonio Dole, Filippos Tourlomousis, Robert C. Chang
Proc. ASME. MSEC2016, Volume 2: Materials; Biomanufacturing; Properties, Applications and Systems; Sustainable Manufacturing, V002T03A003, June 27–July 1, 2016
Publisher: American Society of Mechanical Engineers
Paper No: MSEC2016-8588
https://doi.org/10.1115/MSEC2016-8588
View Paper titled, Design of a Skin Grafting Methodology for Burn Wound Using an Additive Biomanufacturing System Guided by Hyperspectral Imaging
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Topics: Biomanufacturing, Design, Imaging, Skin, Biological tissues, Oxygen, Biomedicine, Dimensions, Fibers, Geometry
Proceedings Papers

Towards Resolution Enhancement and Process Repeatability With a Melt Electrospinning Writing Process: Design and Protocol Considerations

Filippos Tourlomousis, Houzhu Ding, Antonio Dole, Robert C. Chang
Proc. ASME. MSEC2016, Volume 2: Materials; Biomanufacturing; Properties, Applications and Systems; Sustainable Manufacturing, V002T03A005, June 27–July 1, 2016
Publisher: American Society of Mechanical Engineers
Paper No: MSEC2016-8774
https://doi.org/10.1115/MSEC2016-8774
View Paper titled, Towards Resolution Enhancement and Process Repeatability With a Melt Electrospinning Writing Process: Design and Protocol Considerations
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Topics: Electrospinning, Process design, Resolution (Optics), Fibers, Manufacturing, Printing, Additive manufacturing, Cultured cells, Design, Extruding
Proceedings Papers

Design of a Personalized Skin Grafting Methodology Using an Additive Biomanufacturing System Guided by 3D Photogrammetry

Houzhu Ding, Filippos Tourlomousis, Azizbek Babakhanov, Robert C. Chang
Proc. ASME. IMECE2015, Volume 2A: Advanced Manufacturing, V02AT02A060, November 13–19, 2015
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2015-51990
https://doi.org/10.1115/IMECE2015-51990
View Paper titled, Design of a Personalized Skin Grafting Methodology Using an Additive Biomanufacturing System Guided by 3D Photogrammetry
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Topics: Biomanufacturing, Design, Photogrammetry, Skin, Three-dimensional models, Additive manufacturing, Computer software, Algorithms, Atomic force microscopy, Biological tissues
Proceedings Papers

2D and 3D Multiscale Computational Modeling of Dynamic Microorgan Devices as Drug Screening Platforms

Filippos Tourlomousis, Robert C. Chang
Proc. ASME. IMECE2015, Volume 3: Biomedical and Biotechnology Engineering, V003T03A051, November 13–19, 2015
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2015-52734
https://doi.org/10.1115/IMECE2015-52734
View Paper titled, 2D and 3D Multiscale Computational Modeling of Dynamic Microorgan Devices as Drug Screening Platforms
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Topics: Computer simulation, Drugs, Microfluidics, Modeling, Flow (Dynamics), Hydrogels, Liver, Creeping flow, Density, Design
Proceedings Papers

A Novel Melt Electrospinning System for Studying Cell Substrate Interactions

Filippos Tourlomousis, Azizbek Babakhanov, Houzhu Ding, Robert C. Chang
Proc. ASME. MSEC2015, Volume 2: Materials; Biomanufacturing; Properties, Applications and Systems; Sustainable Manufacturing, V002T03A006, June 8–12, 2015
Publisher: American Society of Mechanical Engineers
Paper No: MSEC2015-9443
https://doi.org/10.1115/MSEC2015-9443
View Paper titled, A Novel Melt Electrospinning System for Studying Cell Substrate Interactions
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Topics: Electrospinning, Design, Fibers, Manufacturing, Biomaterials, Biomedicine, Biomimetics, Dimensions, Heating, Melt processing
Proceedings Papers

Computational Modeling of 3D Printed Tissue-on-a-Chip Microfluidic Devices as Drug Screening Platforms

Filippos Tourlomousis, Robert C. Chang
Proc. ASME. IMECE2014, Volume 3: Biomedical and Biotechnology Engineering, V003T03A038, November 14–20, 2014
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2014-38454
https://doi.org/10.1115/IMECE2014-38454
View Paper titled, Computational Modeling of 3D Printed Tissue-on-a-Chip Microfluidic Devices as Drug Screening Platforms
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Topics: Additive manufacturing, Biological tissues, Computer simulation, Drugs, Microfluidics, Flow (Dynamics), Liver, Shear stress, Diffusion (Physics), Modeling