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Paul A. Iaizzo
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Proceedings Papers

The Micro-CT Scanning of Human Hearts with Previously Implanted Clinical Devices: Subsequent Generation of High-Resolution Computational Models

Audrey Wethington, Sophia Boman, Amanda DeVos, MS, John Brigham, MLIS, Paul A. Iaizzo, PHD
Proc. ASME. DMD2024, 2024 Design of Medical Devices Conference, V001T01A002, April 8–10, 2024
Publisher: American Society of Mechanical Engineers
Paper No: DMD2024-1027
https://doi.org/10.1115/DMD2024-1027
View Paper titled, The Micro-CT Scanning of Human Hearts with Previously Implanted Clinical Devices: Subsequent Generation of High-Resolution Computational Models
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Topics: Computer simulation, Pacemakers, Resolution (Optics), Valves, Biological tissues, Cardiovascular devices, Databases, Diseases, Imaging, Medical devices
Proceedings Papers

Micro Computed Tomography Imaging and Subsequent Quantifications of the Associated Changes in Cardiac Anatomies Relative to Various Methods of Specimen Fixation

Amanda N. DeVos, Paul A. Iaizzo
Proc. ASME. DMD2024, 2024 Design of Medical Devices Conference, V001T01A006, April 8–10, 2024
Publisher: American Society of Mechanical Engineers
Paper No: DMD2024-1075
https://doi.org/10.1115/DMD2024-1075
View Paper titled, Micro Computed Tomography Imaging and Subsequent Quantifications of the Associated Changes in Cardiac Anatomies Relative to Various Methods of Specimen Fixation
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Topics: Computerized tomography, Imaging, Biological tissues, Anatomy, Aorta, Blood, Errors, Resolution (Optics), Testing, Three-dimensional models
Proceedings Papers

Effect of Myocardial Postconditioning with Polyunsaturated Fatty Acids on the Hemodynamics of Reanimated Swine Hearts

Samanta Toczyl, Jörg Reifart, Paul A Iaizzo
Proc. ASME. DMD2024, 2024 Design of Medical Devices Conference, V001T08A009, April 8–10, 2024
Publisher: American Society of Mechanical Engineers
Paper No: DMD2024-1072
https://doi.org/10.1115/DMD2024-1072
View Paper titled, Effect of Myocardial Postconditioning with Polyunsaturated Fatty Acids on the Hemodynamics of Reanimated Swine Hearts
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Topics: Hemodynamics, Blood, Damage, Emulsions, Heart failure, Oxygen, Physiology, Polishing equipment, Surgery, Wounds
Proceedings Papers

Methods for Simultaneously Obtaining Endocardial and Epicardial Electrophysiology Maps from Reanimated Swine Hearts

Neal Duong, Paul A. Iaizzo
Proc. ASME. DMD2024, 2024 Design of Medical Devices Conference, V001T01A001, April 8–10, 2024
Publisher: American Society of Mechanical Engineers
Paper No: DMD2024-1024
https://doi.org/10.1115/DMD2024-1024
View Paper titled, Methods for Simultaneously Obtaining Endocardial and Epicardial Electrophysiology Maps from Reanimated Swine Hearts
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Topics: Electrophysiology
Proceedings Papers

Coronary Access and Perfusion Following Transcatheter Aortic Valve Replacement: The Effects of Relative Coronary Ostium Positioning

Michael Bielecki, Samuel Belding, Paul A. Iaizzo
Proc. ASME. DMD2024, 2024 Design of Medical Devices Conference, V001T01A003, April 8–10, 2024
Publisher: American Society of Mechanical Engineers
Paper No: DMD2024-1047
https://doi.org/10.1115/DMD2024-1047
View Paper titled, Coronary Access and Perfusion Following Transcatheter Aortic Valve Replacement: The Effects of Relative Coronary Ostium Positioning
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Topics: Valves
Journal Articles

A Computational Pipeline for Patient-Specific Prediction of the Postoperative Mitral Valve Functional State

Hao Liu, Natalie T. Simonian, Alison M. Pouch, Paul A. Iaizzo, Joseph H. Gorman, III, Robert C. Gorman, Michael S. Sacks
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. November 2023, 145(11): 111002.
Paper No: BIO-23-1060
https://doi.org/10.1115/1.4062849
Published Online: August 2, 2023
View Article titled, A Computational Pipeline for Patient-Specific Prediction of the Postoperative Mitral Valve Functional State
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Topics: Geometry, Valves, Simulation, Pipelines, Maintenance, Calibration, Imaging
Proceedings Papers

ANALYSES OF THE DEVICE-TISSUE INTERFACES OF PREVIOUSLY IMPLANTED STENTS WITHIN PERFUSION-FIXED HUMAN HEARTS UTIILIZING MICRO COMPUTED TOMOGRAPHY

Amanda N. DeVos, Paul A. Iaizzo
Proc. ASME. DMD2023, 2023 Design of Medical Devices Conference, V001T01A005, April 17–19, 2023
Publisher: American Society of Mechanical Engineers
Paper No: DMD2023-4061
https://doi.org/10.1115/DMD2023-4061
View Paper titled, ANALYSES OF THE DEVICE-TISSUE INTERFACES OF PREVIOUSLY IMPLANTED STENTS WITHIN PERFUSION-FIXED HUMAN HEARTS UTIILIZING MICRO COMPUTED TOMOGRAPHY
Open the PDF for ANALYSES OF THE DEVICE-TISSUE INTERFACES OF PREVIOUSLY IMPLANTED STENTS WITHIN PERFUSION-FIXED HUMAN HEARTS UTIILIZING MICRO COMPUTED TOMOGRAPHY in another window
Proceedings Papers

DETECTING PULMONARY EDEMA THROUGHOUT EX VIVO LUNG PERFUSION

Ryan Nadybal, Andrew Wang, Paul A. Iaizzo
Proc. ASME. DMD2023, 2023 Design of Medical Devices Conference, V001T09A007, April 17–19, 2023
Publisher: American Society of Mechanical Engineers
Paper No: DMD2023-4133
https://doi.org/10.1115/DMD2023-4133
View Paper titled, DETECTING PULMONARY EDEMA THROUGHOUT EX VIVO LUNG PERFUSION
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Proceedings Papers

BAILOUT POST-TAVR PCI TECHNIQUES IN REANIMATED SWINE AND HUMAN HEARTS: PROCEDURAL IMAGING AND POST-PROCEDURAL MODELING TECHNIQUES

Michael A. Bielecki, Amanda N. DeVos, Paul A. Iaizzo
Proc. ASME. DMD2023, 2023 Design of Medical Devices Conference, V001T01A003, April 17–19, 2023
Publisher: American Society of Mechanical Engineers
Paper No: DMD2023-2988
https://doi.org/10.1115/DMD2023-2988
View Paper titled, BAILOUT POST-TAVR PCI TECHNIQUES IN REANIMATED SWINE AND HUMAN HEARTS: PROCEDURAL IMAGING AND POST-PROCEDURAL MODELING TECHNIQUES
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Proceedings Papers

Assessment of Contractile Forces of Swine Skeletal Muscle Following Irreversible Electroporation Therapy

David A Ramirez, Paul A Iaizzo
Proc. ASME. DMD2022, 2022 Design of Medical Devices Conference, V001T01A007, April 11–14, 2022
Publisher: American Society of Mechanical Engineers
Paper No: DMD2022-1070
https://doi.org/10.1115/DMD2022-1070
View Paper titled, Assessment of Contractile Forces of Swine Skeletal Muscle Following Irreversible Electroporation Therapy
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Proceedings Papers

Utilization of Computational Modeling and 3D Printing for Pre-Procedural Planning of an LVAD Exchange Surgery

Amanda DeVos, David A Ramirez, Celia Gonzalez, Andrew Shaffer, Paul A Iaizzo
Proc. ASME. DMD2022, 2022 Design of Medical Devices Conference, V001T02A008, April 11–14, 2022
Publisher: American Society of Mechanical Engineers
Paper No: DMD2022-1068
https://doi.org/10.1115/DMD2022-1068
View Paper titled, Utilization of Computational Modeling and 3D Printing for Pre-Procedural Planning of an LVAD Exchange Surgery
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Topics: Additive manufacturing, Computer simulation, Surgery
Proceedings Papers

Development of an Epicardial Mapping Tank for Noninvasive Electrical Mapping of Ex Vivo Large Mammalian Hearts

Renee C. Brigham, Erik R. Donley, Paul A. Iaizzo
Proc. ASME. DMD2022, 2022 Design of Medical Devices Conference, V001T01A006, April 11–14, 2022
Publisher: American Society of Mechanical Engineers
Paper No: DMD2022-1069
https://doi.org/10.1115/DMD2022-1069
View Paper titled, Development of an Epicardial Mapping Tank for Noninvasive Electrical Mapping of Ex Vivo Large Mammalian Hearts
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Topics: Ablation (Vaporization technology), Arrhythmias, Computer software, Design, Electrodes, Electrophysiology, Geometry, Heat conduction, Medical devices, Physiology
Proceedings Papers

Aberrant Coronary Artery: A Rare Congenital Anomaly Examined Through Pre- And Post-Procedural 3D Anatomical Modeling

Amanda C. Tenhoff, Tinen L. Iles, Paul A. Iaizzo, Robroy MacIver
Proc. ASME. DMD2022, 2022 Design of Medical Devices Conference, V001T02A007, April 11–14, 2022
Publisher: American Society of Mechanical Engineers
Paper No: DMD2022-1061
https://doi.org/10.1115/DMD2022-1061
View Paper titled, Aberrant Coronary Artery: A Rare Congenital Anomaly Examined Through Pre- And Post-Procedural 3D Anatomical Modeling
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Topics: Coronary arteries, Diseases, Modeling, Virtual reality
Proceedings Papers

Development of a Dilated Cardiomyopathy Heart Failure Model Employing High-Rate Pacing via an Implantable Leadless Pacemaker: Utilized for in Situ and Ex Vivo Investigations

Emma Schinstock, Michael Bielecki, D’Anne Kudlik, Michael Eggen, Paul A. Iaizzo
Proc. ASME. DMD2022, 2022 Design of Medical Devices Conference, V001T01A005, April 11–14, 2022
Publisher: American Society of Mechanical Engineers
Paper No: DMD2022-1064
https://doi.org/10.1115/DMD2022-1064
View Paper titled, Development of a Dilated Cardiomyopathy Heart Failure Model Employing High-Rate Pacing via an Implantable Leadless Pacemaker: Utilized for in Situ and Ex Vivo Investigations
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Topics: Heart failure, Pacemakers
Proceedings Papers

The Use of a Pulsatile Perfusion Apparatus for the Assessment of Aortic Valve Function within Formalin Fixed Human Hearts: Pre- And Post-Tavr Implantation with Subsequent Micro-CT Analyses

Michael A. Bielecki, Paul A. Iaizzo
Proc. ASME. DMD2022, 2022 Design of Medical Devices Conference, V001T06A005, April 11–14, 2022
Publisher: American Society of Mechanical Engineers
Paper No: DMD2022-1059
https://doi.org/10.1115/DMD2022-1059
View Paper titled, The Use of a Pulsatile Perfusion Apparatus for the Assessment of Aortic Valve Function within Formalin Fixed Human Hearts: Pre- And Post-Tavr Implantation with Subsequent Micro-CT Analyses
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Topics: Echocardiography, Valves
Proceedings Papers

Evaluating the Potential Susceptibilities of Swine Bronchi to Colateral Damage from Applied Cryoablation

Weston Upchurch, David Ramirez, Paul A. Iaizzo
Proc. ASME. DMD2021, 2021 Design of Medical Devices Conference, V001T02A003, April 12–15, 2021
Publisher: American Society of Mechanical Engineers
Paper No: DMD2021-1046
https://doi.org/10.1115/DMD2021-1046
View Paper titled, Evaluating the Potential Susceptibilities of Swine Bronchi to Colateral Damage from Applied Cryoablation
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Topics: Ablation (Vaporization technology), Damage
Proceedings Papers

Altered Vascular Contractilities Associated with the Applications of Irreversible Electroporation

David A Ramirez, Weston Upchurch, Paul A Iaizzo
Proc. ASME. DMD2021, 2021 Design of Medical Devices Conference, V001T02A006, April 12–15, 2021
Publisher: American Society of Mechanical Engineers
Paper No: DMD2021-1057
https://doi.org/10.1115/DMD2021-1057
View Paper titled, Altered Vascular Contractilities Associated with the Applications of Irreversible Electroporation
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Topics: Electroporation, Patient treatment, Ablation (Vaporization technology), Biological tissues, Damage, Muscle, Myocardium
Proceedings Papers

Utilization of Optical Coherence Tomography to Assess Coronary Vessel Constriction after Ablation

David A Ramirez, Thomas F Valenzuela, Renee C Brigham, Paul A Iaizzo
Proc. ASME. DMD2021, 2021 Design of Medical Devices Conference, V001T02A010, April 12–15, 2021
Publisher: American Society of Mechanical Engineers
Paper No: DMD2021-1080
https://doi.org/10.1115/DMD2021-1080
View Paper titled, Utilization of Optical Coherence Tomography to Assess Coronary Vessel Constriction after Ablation
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Topics: Ablation (Vaporization technology), Coherence (Optics), Electroporation, Vessels
Proceedings Papers

Interactive Computational Medical Device Deployments within Virtual Reality

Alex J. Deakyne, Paul A. Iaizzo
Proc. ASME. DMD2021, 2021 Design of Medical Devices Conference, V001T03A002, April 12–15, 2021
Publisher: American Society of Mechanical Engineers
Paper No: DMD2021-1014
https://doi.org/10.1115/DMD2021-1014
View Paper titled, Interactive Computational Medical Device Deployments within Virtual Reality
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Topics: Medical devices, Virtual reality
Proceedings Papers

Assessing the Complexity of Human Ventricular Anatomy: Computational Placement of Mapping Catheters in Perfusion- Fixed Human Hearts

Renee C. Brigham, Rachel L. Gasser, Tinen L. Iles, Paul A. Iaizzo
Proc. ASME. DMD2021, 2021 Design of Medical Devices Conference, V001T02A008, April 12–15, 2021
Publisher: American Society of Mechanical Engineers
Paper No: DMD2021-1069
https://doi.org/10.1115/DMD2021-1069
View Paper titled, Assessing the Complexity of Human Ventricular Anatomy: Computational Placement of Mapping Catheters in Perfusion- Fixed Human Hearts
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Topics: Ablation (Vaporization technology), Anatomy, Catheters