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Journal Articles

2022 Summer Biomechanics, Bioengineering, and Biotransport Conference Student Paper Competition

Joao S. Soares
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Guest Editorial
J Biomech Eng. August 2023, 145(8): 080302.
Paper No: BIO-23-1212
https://doi.org/10.1115/1.4062742
Published Online: June 28, 2023
View Article titled, 2022 Summer Biomechanics, Bioengineering, and Biotransport Conference Student Paper Competition
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Topics: Biomechanics, Cardiovascular system, Students, Bioengineering, Biotransport, Biological fluid dynamics, Biosensors, Solid mechanics, Tissue engineering, Biological tissues
Journal Articles

Assessing Patient-Specific Mechanical Properties of Aortic Wall and Peri-Aortic Structures From In Vivo DENSE Magnetic Resonance Imaging Using an Inverse Finite Element Method and Elastic Foundation Boundary Conditions

Johane H. Bracamonte, John S. Wilson, Joao S. Soares
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. December 2020, 142(12): 121011.
Paper No: BIO-20-1122
https://doi.org/10.1115/1.4047721
Published Online: September 8, 2020
View Article titled, Assessing Patient-Specific Mechanical Properties of Aortic Wall and Peri-Aortic Structures From In Vivo DENSE Magnetic Resonance Imaging Using an Inverse Finite Element Method and Elastic Foundation Boundary Conditions
Open the PDF for Assessing Patient-Specific Mechanical Properties of Aortic Wall and Peri-Aortic Structures From In Vivo DENSE Magnetic Resonance Imaging Using an Inverse Finite Element Method and Elastic Foundation Boundary Conditions in another window
Topics: Boundary-value problems, Displacement, Finite element methods, Magnetic resonance imaging, Stiffness, Aorta, Biological tissues, Traction, Materials properties, Mechanical properties
Journal Articles

Multiscale Modeling of Flow Induced Thrombogenicity With Dissipative Particle Dynamics and Molecular Dynamics

Danny Bluestein, João S. Soares, Peng Zhang, Chao Gao, Seetha Pothapragada, Na Zhang, Marvin J. Slepian, Yuefan Deng
Journal: Journal of Medical Devices
Publisher: ASME
Article Type: Frontiers Abstracts
J. Med. Devices. December 2013, 7(4): 024502.
Paper No: MED-13-1211
https://doi.org/10.1115/1.4027347
Published Online: April 28, 2014
View Article titled, Multiscale Modeling of Flow Induced Thrombogenicity With Dissipative Particle Dynamics and Molecular Dynamics
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Topics: Flow (Dynamics), Molecular dynamics, Multiscale modeling, Particle dynamics, Platelets
Proceedings Papers

Constitutive Model of Biodegradable Non-Linear Polymeric Materials for Applications in the Biomedical Field

Joao S. Soares, James E. Moore, Kumbakonam R. Rajagopal
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 733-734, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176484
https://doi.org/10.1115/SBC2007-176484
View Paper titled, Constitutive Model of Biodegradable Non-Linear Polymeric Materials for Applications in the Biomedical Field
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Topics: Biodegradation, Biomedicine, Constitutive equations, Polymers, Drug delivery systems, Patient treatment, Tissue engineering
Proceedings Papers

Modeling the Role of Oscillatory Flow and Dynamic Mechanical Conditioning on Dense Connective Tissue Formation in Mesenchymal Stem Cell Derived Heart Valve Tissue Engineering

João S. Soares, Trung L. Le, Fotis Sotiropoulos, Michael S. Sacks
Proc. ASME. FMD2013, ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation, V001T07A003, September 11–13, 2013
Publisher: American Society of Mechanical Engineers
Paper No: FMD2013-16165
https://doi.org/10.1115/FMD2013-16165
View Paper titled, Modeling the Role of Oscillatory Flow and Dynamic Mechanical Conditioning on Dense Connective Tissue Formation in Mesenchymal Stem Cell Derived Heart Valve Tissue Engineering
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Topics: Biological tissues, Flow (Dynamics), Modeling, Stem cells, Tissue engineering, Valves, Bioreactors, Computational fluid dynamics, Bioengineering, Boundary-value problems
Proceedings Papers

Multiscale Modeling of Flow Induced Thrombogenicity With Dissipative Particle Dynamics (DPD) and Molecular Dynamics (MD)

Danny Bluestein, João S. Soares, Peng Zhang, Chao Gao, Seetha Pothapragada, Na Zhang, Marvin J. Slepian, Yuefan Deng
Proc. ASME. FMD2013, ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation, V001T07A005, September 11–13, 2013
Publisher: American Society of Mechanical Engineers
Paper No: FMD2013-16176
https://doi.org/10.1115/FMD2013-16176
View Paper titled, Multiscale Modeling of Flow Induced Thrombogenicity With Dissipative Particle Dynamics (DPD) and Molecular Dynamics (MD)
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Topics: Flow (Dynamics), Molecular dynamics, Multiscale modeling, Particle dynamics, Platelets, Thrombosis, Blood, Blood flow, Erythrocytes, Fluids
Journal Articles

Thromboresistance Comparison of the HeartMate II Ventricular Assist Device With the Device Thrombogenicity Emulation-Optimized HeartAssist 5 VAD

Wei-Che Chiu, Gaurav Girdhar, Michalis Xenos, Yared Alemu, Jõao S. Soares, Shmuel Einav, Marvin Slepian, Danny Bluestein
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2014, 136(2): 021014.
Paper No: BIO-13-1418
https://doi.org/10.1115/1.4026254
Published Online: February 5, 2014
View Article titled, Thromboresistance Comparison of the HeartMate II Ventricular Assist Device With the Device Thrombogenicity Emulation-Optimized HeartAssist 5 VAD
Open the PDF for Thromboresistance Comparison of the HeartMate II Ventricular Assist Device With the Device Thrombogenicity Emulation-Optimized HeartAssist 5 VAD in another window
Topics: Computer simulation, Flow (Dynamics), Impellers, Platelets, Thrombosis, Ventricular assist devices, Stress
Proceedings Papers

Multiscale Modeling of Flow Induced Thrombogenicity Using Dissipative Particle Dynamics and Coarse Grained Molecular Dynamics

Peng Zhang, Jawaad Sheriff, João S. Soares, Chao Gao, Seetha Pothapragada, Na Zhang, Yuefan Deng, Danny Bluestein
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT36A002, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14187
https://doi.org/10.1115/SBC2013-14187
View Paper titled, Multiscale Modeling of Flow Induced Thrombogenicity Using Dissipative Particle Dynamics and Coarse Grained Molecular Dynamics
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Topics: Flow (Dynamics), Molecular dynamics, Multiscale modeling, Particle dynamics, Platelets, Thrombosis, Blood, Blood flow, Erythrocytes, Fluids
Proceedings Papers

Simulation of the Role of Oscillatory Shear Stress on Mesenchymal Stem Cell Proliferation and Extracellular Matrix Production in Engineered Heart Valve Tissue Formation

João S. Soares, Trung B. Le, Fotis Sotiropoulos, Michael S. Sacks
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT15A001, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14180
https://doi.org/10.1115/SBC2013-14180
View Paper titled, Simulation of the Role of Oscillatory Shear Stress on Mesenchymal Stem Cell Proliferation and Extracellular Matrix Production in Engineered Heart Valve Tissue Formation
Open the PDF for Simulation of the Role of Oscillatory Shear Stress on Mesenchymal Stem Cell Proliferation and Extracellular Matrix Production in Engineered Heart Valve Tissue Formation in another window
Topics: Biological tissues, Shear stress, Simulation, Stem cells, Valves, Biodegradation, Bone, Hemodynamics, Maintenance, Pediatrics
Journal Articles

Modeling the Role of Oscillator Flow and Dynamic Mechanical Conditioning on Dense Connective Tissue Formation in Mesenchymal Stem Cell–Derived Heart Valve Tissue Engineering

João S. Soares, Trung B. Le, Fotis Sotiropoulos, Michael S. Sacks
Journal: Journal of Medical Devices
Publisher: ASME
Article Type: Frontiers Abstracts
J. Med. Devices. December 2013, 7(4): 040927.
Paper No: MED-13-1248
https://doi.org/10.1115/1.4025984
Published Online: December 5, 2013
View Article titled, Modeling the Role of Oscillator Flow and Dynamic Mechanical Conditioning on Dense Connective Tissue Formation in Mesenchymal Stem Cell–Derived Heart Valve Tissue Engineering
Open the PDF for Modeling the Role of Oscillator Flow and Dynamic Mechanical Conditioning on Dense Connective Tissue Formation in Mesenchymal Stem Cell–Derived Heart Valve Tissue Engineering in another window
Topics: Biological tissues, Flow (Dynamics), Modeling, Stem cells, Tissue engineering, Valves
Proceedings Papers

Multiscale Modeling of Flow Induced Thrombogenicity Using Dissipative Particle Dynamics and Molecular Dynamics

Danny Bluestein, João S. Soares, Peng Zhang, Chao Gao, Seetha Pothapragada, Na Zhang, Marvin J. Slepian, Yuefan Deng
Proc. ASME. NEMB2013, ASME 2013 2nd Global Congress on NanoEngineering for Medicine and Biology, V001T05A006, February 4–6, 2013
Publisher: American Society of Mechanical Engineers
Paper No: NEMB2013-93094
https://doi.org/10.1115/NEMB2013-93094
View Paper titled, Multiscale Modeling of Flow Induced Thrombogenicity Using Dissipative Particle Dynamics and Molecular Dynamics
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Topics: Flow (Dynamics), Molecular dynamics, Multiscale modeling, Particle dynamics, Platelets, Thrombosis, Blood, Blood flow, Erythrocytes, Fluids
Proceedings Papers

Mechanics of Deformation-Induced Degradation of Poly(L-Lactic Acid) Endovascular Stents

João S. Soares, James E. Moore, Jr., Kumbakonam R. Rajagopal
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 13-14, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-204161
https://doi.org/10.1115/SBC2009-204161
View Paper titled, Mechanics of Deformation-Induced Degradation of Poly(L-Lactic Acid) Endovascular Stents
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Topics: Deformation, Stents, Biodegradation, Cardiology, Drugs
Proceedings Papers

A Mathematical Model for Shear-Induced Platelet Activation in Response to Time Dependent Shear Stress Histories

João S. Soares, Jawaad Sheriff, Danny Bluestein
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 1305-1306, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80133
https://doi.org/10.1115/SBC2012-80133
View Paper titled, A Mathematical Model for Shear-Induced Platelet Activation in Response to Time Dependent Shear Stress Histories
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Topics: Platelets, Shear (Mechanics), Shear stress, Blood, Cardiovascular system, Damage, Drugs, Heart valve prostheses, Risk, Ventricular assist devices
Proceedings Papers

Evaluation of Platelet Activation Models With Dynamic Shear Stress In Vitro Experiments

Jawaad Sheriff, Michalis Xenos, João S. Soares, Jolyon Jesty, Danny Bluestein
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 883-884, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80134
https://doi.org/10.1115/SBC2012-80134
View Paper titled, Evaluation of Platelet Activation Models With Dynamic Shear Stress In Vitro Experiments
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Topics: Platelets, Shear stress, Blood, Flow (Dynamics), Shear (Mechanics), Diseases, Heart failure, Heart valve prostheses, Optimization, Patient treatment
Journal Articles

Modeling of Deformation-Accelerated Breakdown of Polylactic Acid Biodegradable Stents

João S. Soares, James E. Moore, Jr., Kumbakonam R. Rajagopal
Journal: Journal of Medical Devices
Publisher: ASME
Article Type: Research Papers
J. Med. Devices. December 2010, 4(4): 041007.
https://doi.org/10.1115/1.4002759
Published Online: December 6, 2010
View Article titled, Modeling of Deformation-Accelerated Breakdown of Polylactic Acid Biodegradable Stents
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Topics: Biodegradation, Deformation, Stents, Stress, Polymers, Design