Generating liquid droplets is ideal for many applications including respiratory drug delivery because the droplets have uniform properties and can be easily controlled, sampled, and analyzed. In this study, a micropump-based droplet generator is proposed to produce the liquid droplets of micron to nano size. Numerical simulations were carried out to evaluate the ability of the proposed droplet generator device to produce liquid droplets. The velocity and diameter of the droplets generated by the droplet generator device were calculated, and the performance of the device’s flow rate and power consumption was evaluated. The effects of actuation frequency, actuation modes, and nozzle geometry on the performance of the device were investigated. Results showed that the proposed device can produce micron-/nano-sized liquid droplets with low power and the advantages of the proposed droplet generator device over traditional devices were discussed.
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August 2011
Research Papers
Generating Nanoparticles for Respiratory Drug Delivery
Guoguang Su,
Guoguang Su
Department of Mechanical Engineering,
Virginia Commonwealth University
, Richmond, VA 23284
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Ramana M. Pidaparti
Ramana M. Pidaparti
Department of Mechanical Engineering,
e-mail: rmpidaparti@vcu.edu
Virginia Commonwealth University
, Richmond, VA 23284
Search for other works by this author on:
Guoguang Su
Department of Mechanical Engineering,
Virginia Commonwealth University
, Richmond, VA 23284
Ramana M. Pidaparti
Department of Mechanical Engineering,
Virginia Commonwealth University
, Richmond, VA 23284e-mail: rmpidaparti@vcu.edu
J. Nanotechnol. Eng. Med. Aug 2011, 2(3): 031010 (8 pages)
Published Online: January 20, 2012
Article history
Received:
July 7, 2011
Revised:
August 22, 2011
Online:
January 20, 2012
Published:
January 20, 2012
Citation
Su, G., and Pidaparti, R. M. (January 20, 2012). "Generating Nanoparticles for Respiratory Drug Delivery." ASME. J. Nanotechnol. Eng. Med. August 2011; 2(3): 031010. https://doi.org/10.1115/1.4005488
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