A novel translating bed total body irradiation treatment delivery technique that employs dynamically shaped beams is presented. The patient is translated along the floor on a moving bed through a stationary radiation beam and the shape of the radiation beam is changed dynamically as the patient is moved through it, enabling compensation for local variations in patient thickness and tissue density. We demonstrate that the use of dynamically shaped beams results in greatly improved dose homogeneity compared with standard techniques, which use a single static beam shape. Along a representative dose profile through the lungs of a mock-human body, the maximum range of dose deviation from the average is 5.6% (from to ) for the dynamic beam technique compared with 12.8% (from to ) for the static beam technique. A novel, dual-interlock system that prevents bed motion when the radiation beam is stopped and stops the radiation beam when the bed motor is stopped has also been developed. The dual-interlock not only enhances the safety of the treatment but also ensures accuracy in the delivery of the treatment.
Skip Nav Destination
e-mail: derek.brown@albertahealthservices.ca
Article navigation
September 2010
Research Papers
A Novel Translational Total Body Irradiation Technique
Derek W. Brown,
Derek W. Brown
Department of Medical Physics,
e-mail: derek.brown@albertahealthservices.ca
Tom Baker Cancer Centre
, Calgary, AB, Canada T2N 4N2; Department of Physics and Astronomy, University of Calgary
, Calgary, AB, Canada T2N 1N4; Department of Radiation Oncology, University of Calgary
, Calgary, AB, Canada
Search for other works by this author on:
Kurt Knibutat,
Kurt Knibutat
Department of Medical Physics,
Tom Baker Cancer Centre
, Calgary, AB, Canada
Search for other works by this author on:
Nathan Edmonds,
Nathan Edmonds
Department of Medical Physics,
Tom Baker Cancer Centre
, Calgary, AB, Canada
Search for other works by this author on:
Daniel Tom,
Daniel Tom
Department of Medical Physics,
Tom Baker Cancer Centre
, Calgary, AB, Canada
Search for other works by this author on:
Leo Moriarty,
Leo Moriarty
Department of Medical Physics,
Tom Baker Cancer Centre
, Calgary, AB, Canada
Search for other works by this author on:
Peter Hanson,
Peter Hanson
Department of Medical Physics,
Tom Baker Cancer Centre
, Calgary, AB, Canada
Search for other works by this author on:
Mona Udowicz,
Mona Udowicz
Department of Medical Physics,
Tom Baker Cancer Centre
, Calgary, AB, Canada
Search for other works by this author on:
Amjad Hussain,
Amjad Hussain
Department of Medical Physics,
Tom Baker Cancer Centre
, Calgary, AB, Canada; Department of Physics and Astronomy, University of Calgary
, Calgary, AB, Canada
Search for other works by this author on:
Jose Eduardo Villarreal-Barajas,
Jose Eduardo Villarreal-Barajas
Department of Medical Physics,
Tom Baker Cancer Centre
, Calgary, AB, Canada; Department of Physics and Astronomy, University of Calgary
, Calgary, AB, Canada; Department of Radiation Oncology, University of Calgary
, Calgary, AB, Canada
Search for other works by this author on:
Alana Hudson
Alana Hudson
Department of Medical Physics,
Tom Baker Cancer Centre
, Calgary, AB, Canada
Search for other works by this author on:
Derek W. Brown
Department of Medical Physics,
Tom Baker Cancer Centre
, Calgary, AB, Canada T2N 4N2; Department of Physics and Astronomy, University of Calgary
, Calgary, AB, Canada T2N 1N4; Department of Radiation Oncology, University of Calgary
, Calgary, AB, Canadae-mail: derek.brown@albertahealthservices.ca
Kurt Knibutat
Department of Medical Physics,
Tom Baker Cancer Centre
, Calgary, AB, Canada
Nathan Edmonds
Department of Medical Physics,
Tom Baker Cancer Centre
, Calgary, AB, Canada
Daniel Tom
Department of Medical Physics,
Tom Baker Cancer Centre
, Calgary, AB, Canada
Leo Moriarty
Department of Medical Physics,
Tom Baker Cancer Centre
, Calgary, AB, Canada
Peter Hanson
Department of Medical Physics,
Tom Baker Cancer Centre
, Calgary, AB, Canada
Mona Udowicz
Department of Medical Physics,
Tom Baker Cancer Centre
, Calgary, AB, Canada
Amjad Hussain
Department of Medical Physics,
Tom Baker Cancer Centre
, Calgary, AB, Canada; Department of Physics and Astronomy, University of Calgary
, Calgary, AB, Canada
Jose Eduardo Villarreal-Barajas
Department of Medical Physics,
Tom Baker Cancer Centre
, Calgary, AB, Canada; Department of Physics and Astronomy, University of Calgary
, Calgary, AB, Canada; Department of Radiation Oncology, University of Calgary
, Calgary, AB, Canada
Alana Hudson
Department of Medical Physics,
Tom Baker Cancer Centre
, Calgary, AB, CanadaJ. Med. Devices. Sep 2010, 4(3): 031003 (6 pages)
Published Online: August 31, 2010
Article history
Received:
March 5, 2010
Revised:
May 11, 2010
Online:
August 31, 2010
Published:
August 31, 2010
Citation
Brown, D. W., Knibutat, K., Edmonds, N., Tom, D., Moriarty, L., Hanson, P., Udowicz, M., Hussain, A., Villarreal-Barajas, J. E., and Hudson, A. (August 31, 2010). "A Novel Translational Total Body Irradiation Technique." ASME. J. Med. Devices. September 2010; 4(3): 031003. https://doi.org/10.1115/1.4001864
Download citation file:
Get Email Alerts
Cited By
Related Articles
Vision-Based Patient Body Tracking in Helical Tomotherapy
J. Med. Devices (June,2008)
Correlation of HSP70 Expression and Cell Viability Following Thermal Stimulation of Bovine Aortic Endothelial Cells
J Biomech Eng (October,2005)
Applicability of the Dose Spiking Electron Paramagnetic Resonance Method for the Quantitative Measurements of Low Doses in Alanine Dosimetry
ASME J of Nuclear Rad Sci (January,2023)
Related Proceedings Papers
Related Chapters
Validation of Elekta iViewGT A-Si EPID Model for Pre-Treatment Dose Verification of IMRT Fields
International Conference on Advanced Computer Theory and Engineering, 4th (ICACTE 2011)
Characterization and evaluation
Biocompatible Nanomaterials for Targeted and Controlled Delivery of Biomacromolecules
Advances in Computational Modeling of Sound Propagation in the Lungs and Torso with Diagnostic Applications
Biomedical Applications of Vibration and Acoustics in Therapy, Bioeffect and Modeling