Heat transfer characteristics in a latticework duct with various sidewalls are numerically investigated. The crossing angle is 90 deg and the number of subchannels is eleven on both the pressure side and suction side for each latticework duct. The thickness of the ribs is 8 mm and the distance between adjacent ribs is 24 mm. The investigation is conducted for various Reynolds numbers (11,000 to 55,000) and six different sidewalls. Flow structure, pressure drop, and heat transfer characteristics are analyzed. Results revealed that the sidewall has significant effects on heat transfer and flow structure. The triangle-shaped sidewall provides the highest Nusselt number accompanied by the highest friction factor. The sidewall with a slot shows the lowest friction factor and Nusselt number. An increased slot width decreased the Nusselt number and friction factor simultaneously.