It is highly desirable to understand the fluid flow and the heat transfer characteristics of buoyancy-induced micropump and microheat exchanger in microfluidic and thermal systems. In this study, we analytically investigate the fully developed natural convection in an open-ended vertical parallel-plate microchannel with asymmetric wall temperature distributions. Both of the velocity slip and the temperature jump conditions are considered because they have countereffects both on the volume flow rate and the heat transfer rate. Results reveal that in most of the natural convection situations, the volume flow rate at microscale is higher than that at macroscale, while the heat transfer rate is lower. It is, therefore, concluded that the temperature jump condition induced by the effects of rarefaction and fluid-wall interaction plays an important role in slip-flow natural convection.

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