... of tendon is altered, such as in the natural process of aging or with alterations of matrix proteins, such as proteoglycan expression. While changes in re-alignment and mechanical properties have been investigated recently during development, they have not been studied in (1) aged tendons, or (2...

... biological tissues biomechanics boundary-elements methods cellular biophysics deformation elasticity encapsulation finite element analysis optimisation Young's modulus osteoarthritis collagen proteoglycan aggrecan numerical model inverse problem Mow , V. C. , Ratcliffe...

... 2008 biomechanics cellular biophysics compressibility finite element analysis chondron poroelastic collagen proteoglycan finite element method Articular cartilage is the primary load-bearing soft tissue in diarthrodial joints and exhibits apparent viscoelastic responses...

... to differences in proteoglycan content. (a) The percentage error in the estimate of D decreases as more time points are fitted ( n = 11 / bar ; mean + SEM ). (b) The percentage error in the estimate of D decreases as the signal-to-noise ratio increases ( n > 100 / bar...

...Q. Wang; Y. P. Zheng; H. J. Niu; A. F. T. Mak Articular cartilage is a biological weight-bearing tissue covering the bony ends of articulating joints. Negatively charged proteoglycan (PG) in articular cartilage is one of the main factors that govern its compressive mechanical behavior and swelling...

... and did not affect the minimum and equilibrium friction coefficients. Osteoarthritis is characterized by a progressive degradation of the joint’s cartilage that involves loss of proteoglycans, increased hydration, and fibrillation of the matrix ( 29 ). The results of this study indicate...

... to the well studied type I collagen, other important constituents of tendon are the small proteoglycans (PGs). PGs have been shown to vary in concentration within differently loaded areas of tendon, implicating them in specific tendon function. This study measured the mechanical properties of multiple tendon...