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Keywords: cyclic strain
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Journal Articles

The Effect of Cyclic Strain on Human Fibroblasts With Lamin A/C Mutations and Its Relation to Heart Disease

Richard D. H. Tran, Mark Siemens, Cecilia H. H. Nguyen, Alexander R. Ochs, Michael V. Zaragoza, Anna Grosberg
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2020, 142(6): 061002.
Paper No: BIO-19-1042
https://doi.org/10.1115/1.4044091
Published Online: January 23, 2020
... environment are sufficient to cause differences in cells with and without the LMNA mutation. To test this, a stretcher device was used to induce cyclic strain upon cells, and viability/proliferation, cytoskeleton and extracellular matrix organization, and nuclear morphology were quantified. The properties...
View Article titled, The Effect of <span class="search-highlight">Cyclic</span> <span class="search-highlight">Strain</span> on Human Fibroblasts With Lamin A&#x2F;C Mutations and Its Relation to Heart Disease
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Topics: Diseases, Fibroblasts, Statistical analysis, Membranes, Skin
Includes: Supplementary data
Journal Articles

Flexure-Based Device for Cyclic Strain-Mediated Osteogenic Differentiation

Kyung Shin Kang, Young Hun Jeong, Jung Min Hong, Woon-Jae Yong, Jong-Won Rhie, Dong-Woo Cho
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. November 2013, 135(11): 114501.
Paper No: BIO-12-1559
https://doi.org/10.1115/1.4025103
Published Online: September 23, 2013
....1041430304 This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (No. 2010-0018294). We presented here a cyclic strain generator equipped with a customized flexure-based translational nanoactuator. To our knowledge...
View Article titled, Flexure-Based Device for <span class="search-highlight">Cyclic</span> <span class="search-highlight">Strain</span>-Mediated Osteogenic Differentiation
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Topics: Bending (Stress), Generators, Piezoelectric actuators, PLGA, Displacement, Design, Stem cells
Journal Articles

A Novel Device to Apply Controlled Flexion and Extension to the Rat Knee Following Anterior Cruciate Ligament Reconstruction

Mark E. Stasiak, Dan Wiznia, Saif Alzoobaee, Michael C. Ciccotti, Carl W. Imhauser, Clifford Voigt, Peter A. Torzilli, Xiang-Hua Deng, Scott A. Rodeo
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. April 2012, 134(4): 041008.
https://doi.org/10.1115/1.4006341
Published Online: April 27, 2012
... 27 04 2012 27 04 2012 tendon bone healing ACL in vivo cyclic strain mechanical load The anterior cruciate ligament (ACL) is the primary constraint to anterior translation of the tibia and acts as a secondary constraint to axial rotation. It is often injured during athletic...
View Article titled, A Novel Device to Apply Controlled Flexion and Extension to the Rat Knee Following Anterior Cruciate Ligament Reconstruction
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Topics: Anterior cruciate ligament, Cycles, Knee, Stress, Tendons, Bone, Rotation