In this study, the changes in the bone density of human femur model as a result of different loadings were investigated. The model initially consisted of a solid shell representing cortical bone encompassing a cubical network of interconnected rods representing trabecular bone. A computationally efficient program was developed that iteratively changed the structure of trabecular bone by keeping the local stress in the structure within a defined stress range. The stress was controlled by either enhancing existing beam elements or removing beams from the initial trabecular frame structure. Analyses were performed for two cases of homogenous isotropic and transversely isotropic beams. Trabecular bone structure was obtained for three load cases: walking, stair climbing and stumbling without falling. The results indicate that trabecular bone tissue material properties do not have a significant effect on the converged structure of trabecular bone. In addition, as the magnitude of the loads increase, the internal structure becomes denser in critical zones. Loading associated with the stumbling results in the highest density; whereas walking, considered as a routine daily activity, results in the least internal density in different regions. Furthermore, bone volume fraction at the critical regions of the converged structure is in good agreement with previously measured data obtained from combinations of dual X-ray absorptiometry (DXA) and computed tomography (CT). The results indicate that the converged bone architecture consisting of rods and plates are consistent with the natural bone morphology of the femur. The proposed model shows a promising means to understand the effects of different individual loading patterns on the bone density.
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January 2015
Research-Article
Effects of Different Loading Patterns on the Trabecular Bone Morphology of the Proximal Femur Using Adaptive Bone Remodeling
S. Mohammad Ali Banijamali,
S. Mohammad Ali Banijamali
Department of Mechanical
and Industrial Engineering,
and Industrial Engineering,
Northeastern University
,Boston, MA 02115
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Ramin Oftadeh,
Ramin Oftadeh
Department of Mechanical
and Industrial Engineering,
and Industrial Engineering,
Northeastern University
,Boston, MA 02115
Center for Advanced Orthopaedic Studies,
Department of Orthopaedic Surgery,
Beth Israel Deaconess Medical Center,
Department of Orthopaedic Surgery,
Beth Israel Deaconess Medical Center,
Harvard Medical School
,Boston, MA 02215
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Ara Nazarian,
Ara Nazarian
Center for Advanced Orthopaedic Studies,
Department of Orthopaedic Surgery,
Beth Israel Deaconess Medical Center,
Department of Orthopaedic Surgery,
Beth Israel Deaconess Medical Center,
Harvard Medical School
,Boston, MA 02215
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Ruben Goebel,
Ruben Goebel
Sport Science Program,
Qatar University
,Doha 2713
, Qatar
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Ashkan Vaziri,
Ashkan Vaziri
Department of Mechanical
and Industrial Engineering,
and Industrial Engineering,
Northeastern University
,Boston, MA 02115
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Hamid Nayeb-Hashemi
Hamid Nayeb-Hashemi
1
Professor of Mechanical Engineering
Department of Mechanical
and Industrial Engineering,
e-mail: hamid@coe.neu.edu
Department of Mechanical
and Industrial Engineering,
Northeastern University
,334 Snell Engineering Center
,360 Huntington Avenue
,Boston, MA 02115
e-mail: hamid@coe.neu.edu
1Corresponding author.
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S. Mohammad Ali Banijamali
Department of Mechanical
and Industrial Engineering,
and Industrial Engineering,
Northeastern University
,Boston, MA 02115
Ramin Oftadeh
Department of Mechanical
and Industrial Engineering,
and Industrial Engineering,
Northeastern University
,Boston, MA 02115
Center for Advanced Orthopaedic Studies,
Department of Orthopaedic Surgery,
Beth Israel Deaconess Medical Center,
Department of Orthopaedic Surgery,
Beth Israel Deaconess Medical Center,
Harvard Medical School
,Boston, MA 02215
Ara Nazarian
Center for Advanced Orthopaedic Studies,
Department of Orthopaedic Surgery,
Beth Israel Deaconess Medical Center,
Department of Orthopaedic Surgery,
Beth Israel Deaconess Medical Center,
Harvard Medical School
,Boston, MA 02215
Ruben Goebel
Sport Science Program,
Qatar University
,Doha 2713
, Qatar
Ashkan Vaziri
Department of Mechanical
and Industrial Engineering,
and Industrial Engineering,
Northeastern University
,Boston, MA 02115
Hamid Nayeb-Hashemi
Professor of Mechanical Engineering
Department of Mechanical
and Industrial Engineering,
e-mail: hamid@coe.neu.edu
Department of Mechanical
and Industrial Engineering,
Northeastern University
,334 Snell Engineering Center
,360 Huntington Avenue
,Boston, MA 02115
e-mail: hamid@coe.neu.edu
1Corresponding author.
Manuscript received August 8, 2014; final manuscript received November 7, 2014; accepted manuscript posted November 13, 2014; published online December 10, 2014. Assoc. Editor: Blaine Christiansen.
J Biomech Eng. Jan 2015, 137(1): 011011 (8 pages)
Published Online: January 1, 2015
Article history
Received:
August 8, 2014
Revision Received:
November 7, 2014
Accepted:
November 13, 2014
Online:
December 10, 2014
Citation
Ali Banijamali, S. M., Oftadeh, R., Nazarian, A., Goebel, R., Vaziri, A., and Nayeb-Hashemi, H. (January 1, 2015). "Effects of Different Loading Patterns on the Trabecular Bone Morphology of the Proximal Femur Using Adaptive Bone Remodeling." ASME. J Biomech Eng. January 2015; 137(1): 011011. https://doi.org/10.1115/1.4029059
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