Mitigation of Bone Loss by Dynamic Hydraulic Pressure Stimulation in a Rat Disuse Model

Osteoporosis is a skeletal disease resulting in diminished bone mass and altered bone microstructure, which leads to more fragile bones that have higher risk of fractures^[1]. Approximately 44 million people have been diagnosed for osteoporosis nationwide^[2]. It also causes nearly 1.5 million fractures annually. In order to prevent from such bone loss and to enhance bone quality, effective clinical treatments, e.g. using non-pharmacological approach, are in great need.