According to the schematic and properties of a methane hydrate deposit in Shenhu Area of South China Sea in China, the characteristic of hydrate dissociation, water and gas production were simulated with a depressurization method. The effect of hydrate saturation, porosity and permeability et al. on hydrate dissociation was studied, the key controlling factor and difficulty of gas production from hydrate reservoir by depressurization was confirmed.

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