Mixing of analytes and reagents is a critical and difficult step in lab-on-a-chip applications. This paper presents a hybrid approach for mixing two laminar aqueous streams in a microchannel. It consists of patterned geometric features and electrokinetic actuation along the channel for improved mixing performance. The mixer can potentially mix reagents in a fluid medium from deionized water to electrically conductive fluids (0.2 S m−1) with low voltage supplies (3.5 Vrms). The mixing capacity of this hybrid microfluidic mixer is characterized and compared with that of the separate passive and electrokinetic actuations.
- Design Engineering Division and Computers in Engineering Division
Development of a Microfluidic Mixer for Lab-on-a-Chip Applications With Active and Passive Actuations
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Manoocheri, K, & Du, E. "Development of a Microfluidic Mixer for Lab-on-a-Chip Applications With Active and Passive Actuations." Proceedings of the ASME 2010 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. Volume 4: 12th International Conference on Advanced Vehicle and Tire Technologies; 4th International Conference on Micro- and Nanosystems. Montreal, Quebec, Canada. August 15–18, 2010. pp. 447-451. ASME. https://doi.org/10.1115/DETC2010-28894
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