Biocompatible magnetic nano-particles show great potential in bio-magnetic applications. In this work, the feasibility of magnetically labeled immunoassay using bio-compatible magnetic nanoparticles is investigated. To do this, we study the synthesis technologies for magnetic nano-particles Fe3O4, as well as the coating of various bio-probes onto the magnetic nanoparticles to detect bio-targets, such as proteins, virus, etc. Furthermore, the measurement, magnetoreduction assay, for the amount of bio-targets are developed. The results show such merits as high-sensitivity, high-specificity, high-convenience for magnetoreduction assays using magnetic nanoparticles. The whole assay platform is promisingly applied to food inspection, environment monitoring, and even human diagnosis.
- Design Engineering Division and Computers in Engineering Division
Bio-Assays Using Bio-Functionalized Magnetic Nanoparticles
Hong, C, Horng, H, Yang, H, & Yang, S. "Bio-Assays Using Bio-Functionalized Magnetic Nanoparticles." Proceedings of the ASME 2008 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. Volume 4: 20th International Conference on Design Theory and Methodology; Second International Conference on Micro- and Nanosystems. Brooklyn, New York, USA. August 3–6, 2008. pp. 719-722. ASME. https://doi.org/10.1115/DETC2008-49503
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