Biocompatible magnetic nano-particles show great potential in bio-magnetic applications. In this work, the feasibility of magnetically labeled immunoassay using bio-compatible magnetic nanoparticles is investigated. To do this, we study the synthesis technologies for magnetic nano-particles Fe3O4, as well as the coating of various bio-probes onto the magnetic nanoparticles to detect bio-targets, such as proteins, virus, etc. Furthermore, the measurement, magnetoreduction assay, for the amount of bio-targets are developed. The results show such merits as high-sensitivity, high-specificity, high-convenience for magnetoreduction assays using magnetic nanoparticles. The whole assay platform is promisingly applied to food inspection, environment monitoring, and even human diagnosis.
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ASME 2008 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference
August 3–6, 2008
Brooklyn, New York, USA
Conference Sponsors:
- Design Engineering Division and Computers in Engineering Division
ISBN:
978-0-7918-4328-4
PROCEEDINGS PAPER
Bio-Assays Using Bio-Functionalized Magnetic Nanoparticles
Chin-Yih Hong,
Chin-Yih Hong
Nan-Kai Institute of Technology, Nantou, Taiwan
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Herng-Er Horng,
Herng-Er Horng
National Taiwan Normal University, Taipei, Taiwan
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Hong-Chang Yang,
Hong-Chang Yang
National Taiwan University, Taipei, Taiwan
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Shieh-Yueh Yang
Shieh-Yueh Yang
MagQu Company Ltd., Sijhih, Taiwan
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Chin-Yih Hong
Nan-Kai Institute of Technology, Nantou, Taiwan
Herng-Er Horng
National Taiwan Normal University, Taipei, Taiwan
Hong-Chang Yang
National Taiwan University, Taipei, Taiwan
Shieh-Yueh Yang
MagQu Company Ltd., Sijhih, Taiwan
Paper No:
DETC2008-49503, pp. 719-722; 4 pages
Published Online:
July 13, 2009
Citation
Hong, C, Horng, H, Yang, H, & Yang, S. "Bio-Assays Using Bio-Functionalized Magnetic Nanoparticles." Proceedings of the ASME 2008 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. Volume 4: 20th International Conference on Design Theory and Methodology; Second International Conference on Micro- and Nanosystems. Brooklyn, New York, USA. August 3–6, 2008. pp. 719-722. ASME. https://doi.org/10.1115/DETC2008-49503
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