Manufacturing and assembly (geometric) errors affect the positioning precision of manipulators. In six degrees-of-freedom (6DOF) manipulators, geometric error effects can be compensated through suitable calibration procedures. This, in general, is not possible in lower-mobility manipulators. Thus, methods that evaluate such effects must be implemented at the design stage to determine both which workspace region is less affected by these errors and which dimensional tolerances must be assigned to match given positioning-precision requirements. In the literature, such evaluations are mainly tailored on particular architectures, and the proposed techniques are difficult to extend. Here, a general discussion on how to take into account geometric error effects is presented together with a general method to solve this design problem. The proposed method can be applied to any nonoverconstrained architecture. Eventually, as a case study, the method is applied to the analysis of the geometric error effects of the translational parallel manipulator (TPM) Triflex-II.